The NASA Making Earth System Data Records for Use in Research Environments (MEaSUREs) (https://earthdata.nasa.gov/community/community-data-system-programs/measures-projects) Global Food Security-support Analysis Data (GFSAD) data product provides cropland extent data over South America for nominal year 2015 at 30 meter resolution (GFSAD30SACE). The monitoring of global cropland extent is critical for policymaking and provides important baseline data that are used in many agricultural cropland studies pertaining to water sustainability and food security. The GFSAD30SACE data product uses the pixel-based supervised classifier, Random Forest (RF), to retrieve cropland extent from a combination of Landsat 5 Thematic Mapper (TM), Landsat 7 Enhanced Thematic Mapper Plus (ETM+), Landsat 8 Operational Land Imager (OLI) data, and elevation derived from the Shuttle Radar Topography Mission (SRTM) Version 3 data products. Each GFSAD30SACE GeoTIFF file contains a cropland extent layer that defines areas of cropland, non-cropland, and water bodies over a 10° by 10° area.